STUDI FITOKIMIA DAN FARMAKOLOGI DAUN MANGKOKAN (Nothopanax scutellarium)
Keywords:
Nothopanax Scutellarium, phytochemical studies, pharmacology studies
Abstract
Nothopanax Scutellarium (Araliaceae family), commonly known as the leaves of the bowl, is a medicinal plant that has many pharmacological properties. The leaves of this plant have various uses in traditional medicine for a number of diseases. There are so many substances contained in this plant such as flavonoids, saponins, tannins, phenolics, alkaloids, steroids and so on. Several studies have demonstrated the pharmacological exploration of Nothopanax Scutellarium as a Culex sp mosquito larvicide, diuretic, anti-kidney stone solubility, anti-aging, burn healer, anti-oxidant and anti-bacterial which were carried out experimentally both in vivo and in vitro.
References
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Alkandahri, MY., Subarnas, A., dan Berbudi A. Aktivitas Immunomodulator Tanaman Sambiloto (Andrographis paniculata Nees) – Review. Farmaka. 2018; 16(3): 16-21.
Alkandahri, MY., Siahaan PN., Salim, E., and Fatimah, C. AntiInflammatory Activity of Cep-cepan Leaves (Castanopsis costata (Blume) A.DC). International Journal of Current Medical Sciences. 2018; 8(4A): 424-429.
Alkandahri, MY., Berbudi, A., and Subarnas, A. Active Compounds and Antimalaria Properties of some Medicinal Plants in Indonesia – A Review. Systematic Reviews in Pharmacy. 2018; 9(1): 64-69.
Alkandahri, MY., Berbudi, A., Utami, NV., and Subarnas, A. Antimalarial Activity of Extract and Fractions of Castanopsis costata (Blume) A.DC. Avicenna Journal of Phytomedicine. 2019; 9(5): 474-481.
Alkandahri, MY., Maulana, YE., Subarnas, A., Kwarteng, A., and Berbudi, A. Antimalarial Activity of Extract and Fractions of Cayratia trifolia (L.) Domin. International Journal of Pharmaceutical Research. 2020; 12(1): 1435-1441.
Alkandahri, MY., Kusumawati, AH., and Fikayuniar, L. Antibacterial Activity of Zingiber officinale Rhizome. International Journal of Psychosocial Rehabilitation. 2020; 24(7): 3702- 3706.
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Aziz N.K. 2016. Uji Daya Hambat Ekstrak Ekstrak Daun Mangkokan (Nothopanax scutellarium) dan Buah Stroberi (Fragria Sp) Terhadap Bakteri Salmonella typhii dan Escherichia coli. Skripsi. Program Studi Kedokteran ,Univ Prima Indonesia, Medan.
Bangsu Mike. 2017. Formulasi Sediaan Krim Ekstrak Daun Mangkokan (Nothopanax scutellarium Merr.) Sebagai Anti Aging.
Bronaugh. dkk. 2015. Percutaneous Absorbtion:Drug-Cosmetics Mechanism Methodology 4thedition, Available as PDF, Marcel Dekker, United State
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Hanum GR. 2017. Sabun Ekstrak Mangkokan (Nothopanax Scutellaium merr) Sebagai Antibakteri Terhadap Staphylococcus Aureus. Stigma Journal of science.
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Helmi Arifin. 2012. Pengaruh Ekstrak Etanol Daun Mangkokan (Nothopanax scutellarium. Merr) Terhadap Fungsi Hati Dan Kadar Kreatinin Urin Mencit Putih Jantan. Jurnal Farmasi Higea, Vol.3, No. 2.
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Kusumawati, AH., Farhamzah, F., Alkandahri, MY., Sadino, A., Agustina, LS., and Apriana, SD. Antioxidant Activity and Sun Protection Factor of Black Glutinous Rice (Oryza sativa var. glutinosa). Tropical Journal of Natural Product Research. 2021; 5(11): 1958-1961.
Lutpiatina L. Cemaran Staphylococcus aureus dan Pseudomonas aerogenosa pada Steteskop di Rumah Sakit. J Teknologi Lab.
Mahmudah F.L, Atun S. 2017. Uji Aktivitas Antibakteri Dari Ekstrak Etanol Temu Kunci (Boesenbergia Pandurata Roxb) Terhadap Bakteri Streptococcus Mutans. Jurnal Peneliti Saintek. 22 (1):59.
Mitsunaga Jr J., Gragnani A., Ramoz M. 2012. Rat an experimental model for burn: A systematic review. Acta Cir Bras: 27 (6):417-423.
Moenadjat Y. 2016. Luka Bakar: Masalah dan Tatalaksana. Jakarta: UPK Luka Bakar RS Cipto Mangunkusumo.
Monica Revina. dkk. 2018. Efektivitas Ekstrak Daun Mangkokan Terhadap Penyembuhan Luka Bakar Pada Tikus,Vol.7, No.2.
Nielson. et al. 2016. Burns: Pathophysiology Of Systemic Complications and Current Management. Journal Of Burn Care And Research.
Pratika Viogenta, Wahidah LK, Saputri I.H. 2017. Jurnal Farmasi Lampung JFL Jurnal Farmasi Lampung, Vol.6, No.2: 46-55.
Purwaningsih S., Salamah E., Budiarti T.A., 2014, Formulasi Skin Lotion dengan Penambahan Karagenan dan Antioksidan Alami dari Rhizophora Mucronata Lamk.
Ramadan F, Wardatun S, Wiendarlina IY. 1999. Toksisitas Dan Kadar Tanin Serta Flavonoid Ekstrak Etanol Daun Mangkokan (Nothopanax scutellarium merr).
Ramadhani, F. 2016. Uji Sensitivitas Ekstrak Buah Mengkudu (Morindacitri folialinn) dan Ekstrak Daun Mangkok (Nothopanax scutellarium) Terhadap Bakteri Salmonella typhii dan Escherichia coli. Skripsi. Program Studi Kedokteran. Univ. Prima Indonesia. Medan.
Shafirany, MZ., Indawati, I., Sulastri, L., Sadino, A., Kusumawati, AH., and Alkandahri, MY. Antioxidant Activity of Red and Purple Rosella Flower Petals Extract (Hibiscus sabdariffa L.). Journal of Pharmaceutical Research International. 2021; 33(46B): 186-192.
Syamsuni, H. 2012. Farmasetika Dasar dan Hitungan Farmasi. Jakarta: Penerbit Buku Kedokteran EGC. Halaman : 25.
Tarigan, J.,Zuhra,C., Herlince,S. 2008. Skrining Fitokimia Tumbuhan Yang Digunakan Oleh Pedagang Jamu Gendong Untuk Merawat Kulit Wajah Di Kecamatan Medan Baru. Jurnal Biologi Sumatera. Halaman : 1-6.
Tong S.Y.C, Davis J.S, Eichenberger E, Holland T.L, Fowler V.G. 2015. Staphylococcus aureus infections: Epidemiology, pathophysiology, clinical manifestations, and management. Clin Microbiol Rev. 28 (3).
WHO. 2012. Quality Control Methods for Medicinal Plant Materials. Geneva: WHO. Halaman: 33.
Alkandahri, MY., Nisriadi, L., and Salim, E. Secondary Metabolites and Antioxidant Activity of Methanol Extract of Castanopsis costata Leaves. Pharmacology and Clinical Pharmacy Research. 2016; 1(3): 98-102.
Alkandahri, MY., Subarnas, A., dan Berbudi A. Aktivitas Immunomodulator Tanaman Sambiloto (Andrographis paniculata Nees) – Review. Farmaka. 2018; 16(3): 16-21.
Alkandahri, MY., Siahaan PN., Salim, E., and Fatimah, C. AntiInflammatory Activity of Cep-cepan Leaves (Castanopsis costata (Blume) A.DC). International Journal of Current Medical Sciences. 2018; 8(4A): 424-429.
Alkandahri, MY., Berbudi, A., and Subarnas, A. Active Compounds and Antimalaria Properties of some Medicinal Plants in Indonesia – A Review. Systematic Reviews in Pharmacy. 2018; 9(1): 64-69.
Alkandahri, MY., Berbudi, A., Utami, NV., and Subarnas, A. Antimalarial Activity of Extract and Fractions of Castanopsis costata (Blume) A.DC. Avicenna Journal of Phytomedicine. 2019; 9(5): 474-481.
Alkandahri, MY., Maulana, YE., Subarnas, A., Kwarteng, A., and Berbudi, A. Antimalarial Activity of Extract and Fractions of Cayratia trifolia (L.) Domin. International Journal of Pharmaceutical Research. 2020; 12(1): 1435-1441.
Alkandahri, MY., Kusumawati, AH., and Fikayuniar, L. Antibacterial Activity of Zingiber officinale Rhizome. International Journal of Psychosocial Rehabilitation. 2020; 24(7): 3702- 3706.
Andarwulan, N dkk. 2011. Flavonoid Content and Antioxidant Activity Of Vegetables. Journal Food Chem
Ardhie. A.M. 2011. Radikal Bebas dan Peran Antioksidan dalam Mencegah Penuaan. Anti Aging Medicinus.
Aziz N.K. 2016. Uji Daya Hambat Ekstrak Ekstrak Daun Mangkokan (Nothopanax scutellarium) dan Buah Stroberi (Fragria Sp) Terhadap Bakteri Salmonella typhii dan Escherichia coli. Skripsi. Program Studi Kedokteran ,Univ Prima Indonesia, Medan.
Bangsu Mike. 2017. Formulasi Sediaan Krim Ekstrak Daun Mangkokan (Nothopanax scutellarium Merr.) Sebagai Anti Aging.
Bronaugh. dkk. 2015. Percutaneous Absorbtion:Drug-Cosmetics Mechanism Methodology 4thedition, Available as PDF, Marcel Dekker, United State
Buck. D.F.2012. Food Additives User’s Handbook: Antioxidants, J. Smith Blackie, London.
Dalimarta, S.2012. Atlas Tumbuhan Obat Indonesia. Jakarta
Deny. dkk. 2016. Pengguna Vitamin A dan Vitamin C Topikal Dalam Bidang Kosmetik. Andalas: Majalah Kedokteran.
Farhamzah, Kusumawati, AH., Alkandahri, MY., Hidayah, H., Sujana, D., Gunarti, NS., Yuniarsih, N., Apriana, SD., and Agustina, LS. Sun Protection Factor Activity of Black Glutinous Rice Emulgel Extract (Oryza sativa var glutinosa. Indian Journal of Pharmaceutical Education and Research. 2022; 56(1): 302- 310.
Faridatussaadah. dkk.2013 Isolasi Dan Identifikasi Senyawa Flavonoid Dari Daun Mangkokan ( Burm. f ). Pros Farm.
Fauzi. dkk. 2012. Merawat Kulit dan Wajah. Jakarta: PT Elex Media Komputindo.
Gauglitz. dkk 2011. Hypertrophic Scarring and Kelloid: Pathomechanisms and Current & Emerging Treatment Strategies. Mol Med.
Hanum GR. 2017. Sabun Ekstrak Mangkokan (Nothopanax Scutellaium merr) Sebagai Antibakteri Terhadap Staphylococcus Aureus. Stigma Journal of science.
Harbone, J.B 1987. Metode Fitokimia, Penuntun Cara Modern Menganalisa Tumbuhan. Terjemahan Kosasih Padmawinata. Edisi II. Bandung: ITB Press.
Helmi Arifin. 2012. Pengaruh Ekstrak Etanol Daun Mangkokan (Nothopanax scutellarium. Merr) Terhadap Fungsi Hati Dan Kadar Kreatinin Urin Mencit Putih Jantan. Jurnal Farmasi Higea, Vol.3, No. 2.
Ika Aulia Rahmi, Mahdi Jufri, Abdul Mun’im. 2020. Extraction of Quercetin from Nothopanax scutellarium Leaves via Ionic Liquid-based Microwave-assisted Extraction. Pharmacognosy Journal, Vol.12, No.6.
Kusumawati, AH., Farhamzah, F., Alkandahri, MY., Sadino, A., Agustina, LS., and Apriana, SD. Antioxidant Activity and Sun Protection Factor of Black Glutinous Rice (Oryza sativa var. glutinosa). Tropical Journal of Natural Product Research. 2021; 5(11): 1958-1961.
Lutpiatina L. Cemaran Staphylococcus aureus dan Pseudomonas aerogenosa pada Steteskop di Rumah Sakit. J Teknologi Lab.
Mahmudah F.L, Atun S. 2017. Uji Aktivitas Antibakteri Dari Ekstrak Etanol Temu Kunci (Boesenbergia Pandurata Roxb) Terhadap Bakteri Streptococcus Mutans. Jurnal Peneliti Saintek. 22 (1):59.
Mitsunaga Jr J., Gragnani A., Ramoz M. 2012. Rat an experimental model for burn: A systematic review. Acta Cir Bras: 27 (6):417-423.
Moenadjat Y. 2016. Luka Bakar: Masalah dan Tatalaksana. Jakarta: UPK Luka Bakar RS Cipto Mangunkusumo.
Monica Revina. dkk. 2018. Efektivitas Ekstrak Daun Mangkokan Terhadap Penyembuhan Luka Bakar Pada Tikus,Vol.7, No.2.
Nielson. et al. 2016. Burns: Pathophysiology Of Systemic Complications and Current Management. Journal Of Burn Care And Research.
Pratika Viogenta, Wahidah LK, Saputri I.H. 2017. Jurnal Farmasi Lampung JFL Jurnal Farmasi Lampung, Vol.6, No.2: 46-55.
Purwaningsih S., Salamah E., Budiarti T.A., 2014, Formulasi Skin Lotion dengan Penambahan Karagenan dan Antioksidan Alami dari Rhizophora Mucronata Lamk.
Ramadan F, Wardatun S, Wiendarlina IY. 1999. Toksisitas Dan Kadar Tanin Serta Flavonoid Ekstrak Etanol Daun Mangkokan (Nothopanax scutellarium merr).
Ramadhani, F. 2016. Uji Sensitivitas Ekstrak Buah Mengkudu (Morindacitri folialinn) dan Ekstrak Daun Mangkok (Nothopanax scutellarium) Terhadap Bakteri Salmonella typhii dan Escherichia coli. Skripsi. Program Studi Kedokteran. Univ. Prima Indonesia. Medan.
Shafirany, MZ., Indawati, I., Sulastri, L., Sadino, A., Kusumawati, AH., and Alkandahri, MY. Antioxidant Activity of Red and Purple Rosella Flower Petals Extract (Hibiscus sabdariffa L.). Journal of Pharmaceutical Research International. 2021; 33(46B): 186-192.
Syamsuni, H. 2012. Farmasetika Dasar dan Hitungan Farmasi. Jakarta: Penerbit Buku Kedokteran EGC. Halaman : 25.
Tarigan, J.,Zuhra,C., Herlince,S. 2008. Skrining Fitokimia Tumbuhan Yang Digunakan Oleh Pedagang Jamu Gendong Untuk Merawat Kulit Wajah Di Kecamatan Medan Baru. Jurnal Biologi Sumatera. Halaman : 1-6.
Tong S.Y.C, Davis J.S, Eichenberger E, Holland T.L, Fowler V.G. 2015. Staphylococcus aureus infections: Epidemiology, pathophysiology, clinical manifestations, and management. Clin Microbiol Rev. 28 (3).
WHO. 2012. Quality Control Methods for Medicinal Plant Materials. Geneva: WHO. Halaman: 33.
Published
2022-06-30
Section
Articles
