PERAN AMILITE GCK-12H SEBAGAI SURFAKTAN PADA FORMULA SHAMPO: KAJIAN STABILITAS BUSA DAN EFEKTIVITAS PEMBERSIHAN
Abstract
Shampoo functions to clean hair and scalp and is generally formulated using Sodium Lauryl Sulfate (SLS) surfactants, which are associated with irritation and unstable foam. Surfactant selection is therefore a critical factor in shampoo formulation, as it influences foam production, softness, hair moisture retention, environmental friendliness, and cleansing effectiveness. Amino acid–based surfactants such as Amilite GCK-12H offer advantages including low irritation potential, good foam stability, and biocompatibility. This study aimed to evaluate the effect of Amilite GCK-12H concentration on cleaning power and foam stability in shampoo formulations. The study was conducted by formulating shampoos and performing accelerated stability testing, including pH, viscosity, organoleptic properties, spreadability, homogeneity, foam stability, and cleaning effectiveness. Four formulations were prepared: F0 without Amilite GCK-12H, F1 containing 5%, F2 containing 10%, and F3 containing 15% Amilite GCK-12H. Organoleptic evaluation showed stable odor and homogeneity in all formulations, although color changes occurred in samples exposed to sunlight. pH testing indicated that all formulations remained within the acceptable range of 5.0–9.0, despite slight decreases under certain storage conditions. Viscosity increased at room temperature but decreased at elevated temperatures. Homogeneity and spreadability tests met standard requirements for shampoo preparations. Formulation F3 demonstrated the best performance in foam stability and cleaning effectiveness, achieving a cleaning efficiency of 62% on day 30. Overall, Amilite GCK-12H proved effective in producing a stable shampoo formulation with improved foam characteristics and cleansing performance. These findings support its potential application as a mild, high-performance surfactant for sustainable cosmetic shampoo development in future industrial formulations globally.
References
Alam, P. S., Wantoro, A., & Kisworo. (2022). Sistem pakar pemilihan sampo pria dengan menggunakan metode certainty factor. Jurnal Teknologi dan Sistem Informasi (JTSI), 3(4), 21-27. E-ISSN: 2746-369. Tersedia secara online di: http://jim.teknokrat.ac.id/index.php/JTSI
Andriani, L. N., Putra, I. G. N., & Tunas, I. K. (2022). Pengaruh kombinasi sodium lauril sulfat dan natrium klorida terhadap karakteristik sampo ekstrak lidah buaya. Jurnal Riset Kefarmasian Indonesia, 4(3), 366-374.
Anirudh. P., Amina A., (2022), A Review on Interactions between Amino Acids and Surfactants as Well as Their Impacton Corrosion Inhibition, American Chemical Society, ACS Omega, 7, 47471−47489
Asjur, A. V., Saputro, S., Musdar, T. A., & Ikhsan, M. K. (2022). Formulasi dan uji efektivitas shampoo antiketombe minyak atsiri seledri (Apium graveolens) terhadap jamur Candida albicans. Jurnal Sains dan Kesehatan, 4(5), 481-487. Retrieved from https://jsk.farmasi.unmul.ac.id
Ajinomoto OmniChem. (n.d.). AMILITE® GCK-12H. Retrieved October 10, 2023, from https://www.ulprospector.com/en/eu/PersonalCare/Detail/6835/601209/AMILITE-GCK-12H
Bezerra, K.G.O.; Meira, H.M.; Veras, B.O.; Stamford, T.C.M.; Fernandes, E.L.; Converti, A.; Rufino, R.D.; Sarubbo, L.A. Application of Plant Surfactants as Cleaning Agents in Shampoo Formulations. Processes 2023, 11, 879. https://doi.org/ 10.3390/pr11030879 Academic Editors: Ofelia Anjos, Eugenia Gallardo and Raquel P. F. Guiné
Bajaj, S., Sakhuja, N., & Singla, D. (2012). Stability testing of pharmaceutical products. Journal of Applied Pharmaceutical Science, 2(3), 129-138. https://doi.org/10.7324/JAPS.2012.2302
Badan Pengawas Obat dan Makanan. (2020). Pedoman uji stabilitas suplemen kesehatan. Jakarta: BPOM. https://jdih.pom.go.id/download/rule
C. J. Thompson, N. Ainger, P. Starck, O. O. Mykhaylyk, A. J. Ryan, Shampoo Science: A Review of the Physiochemical Processes behind the Function of a Shampoo. Macromol. Chem. Phys. 2023, 224, 2200420. https://doi.org/10.1002/macp.202200420
Cornwell, P.A. (2018), A review of shampoo surfactant technology: consumer benefits, raw materials and recent developments. Int J Cosmet Sci, 40: 16-30. https://doi.org/10.1111/ics.12439
Eryaputri, N. R. A. S., Triannisa, S., Damayanti, A. F., Za’ani, A. J., Fahlevy, M. E., Farhan, M., Amelia, N., Putri, R. N., S, S. F., & Wulanawati, A. (2023). Effect of the addition variations Cocamide Diethanolamine on physical characteristics preparation of citronella oil shampoo. Indonesian Journal of Chemical Science, 12(2). Retrieved from http://journal.unnes.ac.id/sju/index.php/ijcs
Etika, A. (2019). Formulasi dan uji aktivitas sediaan sampo antiketombe perasan jeruk purut (Citrus hystrix DC) terhadap pertumbuhan jamur Candida albicans secara in vitro (Skripsi). Institut Kesehatan Helvetia, Medan.
Fortune Business Insights. (2025). Shampoo market size, share & industry analysis, by product (medicated/special-purpose and non-medicated/regular), by form (liquid, solid, and others), by application (household and commercial), by distribution channel (hypermarkets/supermarkets, convenience stores, online stores, and others), by manufacturers (private label, toll manufacturing, and multinational), and regional forecast, 2025-2032. Retrieved from https://www.fortunebusinessinsights.com/shampoo-market-103432
Gavazzoni Dias MF. Kosmetik rambut: ikhtisar. Int J Trichology. 2015 Januari-Maret; 7(1):2-15. doi: 10.4103/0974-7753.153450. PMID: 25878443; PMCID: PMC4387693.
González-González, O., Ramirez, I. O., Ramirez, B. I., O’Connell, P., Ballesteros, M. P., Torrado, J. J., & Serrano, D. R. (2022). Drug stability: ICH versus accelerated predictive stability studies. Pharmaceutics, 14(11), 2324. https://doi.org/10.3390/pharmaceutics14112324
Lestari, D. A., Juliantoni, Y., & Hasina, R. (2020). Optimasi formula sampo ekstrak daun pacar air (Impatiens balsamina L.) dengan kombinasi natrium lauril sulfat dan cocamide DEA. Sasambo Journal of Pharmacy, 2(1). Retrieved from http://jffk.unram.ac.id/index.php/sjp/index
Listiyawati, G. P. (2021). Formulasi dan uji sifat fisik sampo kombinasi merang padi (Oryza sativa L.) dan ekstrak bunga kenanga (Cananga odorata) (Skripsi). Politeknik Harapan Bersama, Program Studi Diploma Farmasi.
Nafisah, U., Diyan Permata Sari, Y., & Nur Latifah, L. (2023). Formulasi Dan Evaluasi Fisik Sediaan Gel Sampo Minyak Atsiri Bunga Chamomile (Matricaria recucita L.) Dengan Variasi Konsentrasi HPMC. Parapemikir : Jurnal Ilmiah Farmasi, 12(1), 136. https://doi.org/10.30591/pjif.v12i1.4435
Nareswari, T. L., Nurjannah, O., Sari, L. M. N. I., & Syafitri, E. (2023). Pengaruh variasi surfaktan terhadap sifat fisik sampo berbasis minyak serai wangi (Cymbopogon nardus (L.) Rendle) dan ekstrak lidah buaya (Aloe vera).
Nasmety, A. B., Pramesti, K. A., & Septian, I. Z. (2019). Pengaruh konsentrasi Cocamide DEA sebagai surfaktan pada pembuatan sampo ekstrak daun alamanda. Indonesian Journal on Medical Science, 6(2), 78. Retrieved from http://ijmsbm.org
Ningrum, Y. D. A., Roffada, R.-, & Lara, S. P. (2023). Formulasi Dan Uji Karakteristik Fisik Sediaan Sampo Ekstrak Air Kelapa Menggunakan Metode Freeze Drying. INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal), 7(1), 27. https://doi.org/10.21927/inpharnmed.v7i1.3188
Pinheiro, L.; Faustino, C.Amino Acid-Based Surfactants for Biomedical Applications. Application and Characterization of Surfac tants; InTech, 2017
Pravitasari, A. D., Gozali, D., Hendriani, R., & Mustarichie. (2021). Review: Formulasi dan evaluasi sampo berbagai herbal penyubur rambut. Majalah Farmasetika, 6(2), 152-168. https://doi.org/10.24198/mfarmasetika.v6i2.27629
Putri, D. R., Azis, A. D., & Rizqi, M. N. (2023). Analisis rasio keuangan dan financial distress sebelum dan sesudah COVID-19 subsektor food and beverage. Jurnal Maneksi, 12(3), 564.
Salomon, G., & Giordano-Labadie, F. (2022). Surfactant irritations and allergies. European Journal of Dermatology, 32(6), 677-681. doi:10.1684/ejd.2022.4263
Smaniyah, S., Safitri, D. D., & Furqan, M. (2024). Formulasi sediaan shampoo cair ekstrak etanol daun kayu putih (Malaleuca leucadendron L.) dengan carbopol 940 sebagai pengental. Journal of Healthcare Technology and Medicine, 10(1). e-ISSN: 2615-109X. Tersedia secara online di: https://jurnal.uui.ac.id/index.php/JHTM/article/view/4205
Sulhatun, E., Juliati, E., Sylvia, N., Jalaluddin, & Bahr, S. (2020). Formulasi pembuatan shampoo dengan bahan baku minyak kemiri (Aleurites moluccana) untuk kesehatan rambut. Jurnal Teknologi Kimia Unimal, 11(1), 32-42. https://ojs.unimal.ac.id/jtk/index
Tripathy, D. B., Mishra, A., Clark, J., & Farmer, T. (2018). Synthesis, chemistry, physicochemical properties and industrial applications of amino acid surfactants: A review. Comptes Rendus Chimie, 21(2), 112–130. https://doi.org/10.1016/j.crci.2017.11.005
Türk Erbul, B., Orhan, S., & Saka, B. (2023). Formulation Of Mild Shampoos And Investigation Of Possible Prebiotic Effects. Journal Of Immunology And Clinical Microbiology, 8(4), 100–105. Https://Doi.Org/10.58854/Jicm.1400959
Yuhara, N. A. (2024). Formulasi dan Uji Aktivitas Anti Ketombe P. Ovale Shampoo Ekstrak Etanol Daun Murbei (Morus Alba L.). Jurnal Mahasiswa Ilmu Farmasi Dan Kesehatan, 2(1), 116–125. https://doi.org/10.59841/jumkes.v1i3
Yuan, C. L., Xu, Z. Z., Fan, M. X., Liu, H. Y., Xie, Y. H., & Zhu, T. (2014). Study on characteristics and harm of surfactants. Journal of Chemical and Pharmaceutical Research, 6(7), 2233-2237. Diakses dari www.jocpr.com
