PENGARUH PEMBERIAN INFUSA DAN DEKOKTA JAHE MERAH (Zingiber officinale var rubrum) TERHADAP NILAI VISKOSITAS PUTIH TELUR AYAM KAMPUNG SEBAGAI MUKOLITIK

Reyhan Putra Sopyana; Dani Sujana; Yogi Rahman Nugraha; Zahara Farhan

doi:10.36805/9b904a26

Authors

Reyhan Putra Sopyana Program Studi Diploma III Farmasi, Sekolah Tinggi Ilmu Kesehatan Karsa Husada, Garut, Jawa Barat, Indonesia.
Dani Sujana Program Studi Diploma III Farmasi, Sekolah Tinggi Ilmu Kesehatan Karsa Husada, Garut, Jawa Barat, Indonesia.
Yogi Rahman Nugraha Program Studi Diploma III Farmasi, Sekolah Tinggi Ilmu Kesehatan Karsa Husada, Garut, Jawa Barat, Indonesia.
Zahara Farhan Program Studi Diploma III Keperawatan, Sekolah Tinggi Ilmu Kesehatan Karsa Husada, Garut, Jawa Barat, Indonesia.

DOI:

https://doi.org/10.36805/9b904a26

Keywords:

ARI, Red ginger, Mucolytic, Infusion, Decoction

Abstract

Acute Respiratory Tract Infection (ARI) is characterized by productive cough due to mucus accumulation. Synthetic mucolytics such as bromhexine may cause adverse effects, thus prompting the need for herbal alternatives. Red ginger (Zingiber officinale var. rubrum) contains bioactive compounds including gingerol, shogaol, and saponin, which have potential as natural mucolytics. This study aimed to evaluate the mucolytic effect of red ginger infusions and decoctions on the viscosity of native chicken egg white as a mucus model. The research employed an in vitro quasi-experimental design using a post-test only control group. Treatments consisted of red ginger infusions and decoctions at concentrations of 0.25%, 0.50%, and 1%, compared with a positive control (bromhexine), a negative control, and a solvent control. Viscosity was measured using an NDJ-5S viscometer at 0, 30, 60, and 120 minutes, and data were analyzed using the Kruskal–Wallis test (p < 0.05). Results showed that the 0.25% and 0.50% infusions and the 1% decoction significantly and consistently reduced viscosity, with effectiveness approaching that of the positive control. The greatest viscosity reduction was observed at 120 minutes, namely 29.55%, 28.39%, and 27.05%, respectively, while the positive control achieved 30.65%. These findings confirm the potential of red ginger as an effective herbal mucolytic candidate, warranting further development through advanced studies, including toxicity assessments and clinical safety evaluations

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