INDENTIFIKASI PERMASALAHAN TERKAIT PENGOBATAN PADA PASIEN DISLIPIDEMIA KOMORBID DIABETES MELITUS DENGAN TERAPI STATIN DI SALAH SATU RUMAH SAKIT KOTA BANDUNG TAHUN 2023
DOI:
https://doi.org/10.36805/jpx.v9i2.8037Kata Kunci:
Permasalahan terkait pengobatan, Dislipidemia, Diabetes mellitus tipe II, Statin, Keselamatan pasienAbstrak
Dislipidemia dan diabetes melitus (DM) tipe II dapat terjadi bersamaan dan dapat saling memperburuk kondisi pasien. Kompleksitas pengobatan pada pasien dengan komorbiditas yang demikian berpotensi meningkatkan risiko permasalahan terkait pengobatan. Penelitian ini bertujuan untuk mengetahui demografi pasien dislipidemia komorbid DM tipe II di salah satu rumah sakit di Kota Bandung tahun 2023 serta gambaran kejadian permasalahan pengobatannya. Penelitian deskriptif ini meninjau 92 rekam medis pasien yang sesuai dengan kriteria penelitian, metode yang digunakan untuk mengidentifikasi permasalahan terkait pengobatan mengacu pada Basger et al. 2015. Hasil menunjukkan bahwa pasien dislipidemia komorbid DM tipe II dengan terapi statin didominasi oleh perempuan (55,43%) dan lanjut usia (59,78%). Kejadian permasalahan terkait pengobatan terbanyak adalah pada sub kategori kombinasi obat yang tidak sesuai. Terdapat 78 kasus mengakibatkan peningkatan efek terapeutik dan yang paling umum adalah terkait peresepan lansoprazole dengan atorvastatin; 55 kasus interaksi yang mengakibatkan penurunan efek terapeutik, dimana yang paling umum adalah terkait peresepan clopidogrel dengan atorvastatin. Ada 4 kasus yang mengakibatkan reaksi hipersensitivitas yaitu melibatkan allopurinol dan obat antihipertensi. Dapat disimpulkan bahwa intervensi farmasi klinik dalam meninjau perawatan pasien dengan mempertimbangkan risiko dan manfaat dari kombinasi yang demikian bagi pasien
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