UJI MUTU SIMPLISIA DAN EKSTRAK ETANOL 96% RIMPANG JAHE (Zingiber officinale Roscoe)

Mega Efrilia; Pra Panca Bayu Chandra; Santi Endrawati

doi:10.36805/jpx.v9i1.6817

Mega Efrilia Prodi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA, Jakarta Timur, DKI Jakarta, Indonesia
Pra Panca Bayu Chandra Prodi Farmasi, Sekolah Tinggi Ilmu Kesehatan IKIFA, Jakarta Timur, DKI Jakarta, Indonesia
Santi Endrawati Prodi Farmasi, Fakultas Sains, Farmasi dan Kesehatan, Universitas Mathla’ul Anwar, Pandeglang, Banten, Indonesia

DOI: https://doi.org/10.36805/jpx.v9i1.6817

Keywords: Simplicia quality test, Extract quality test, Ginger rhizome

Abstract

Ginger (Zingiber officinale Roscoe) has long been commonly consumed as a spice and traditional medicine. The aim of the research was to test the quality of simplicia and ginger rhizome extract. The testing procedure consists of preliminary quality testing, testing specific and non-specific parameters. Fresh ginger rhizomes are processed to become simplicia powder. The simplicia was extracted using the maceration method using 96% ethanol solvent, then concentrated until a thick extract was obtained. Simplicia and extracts are subjected to quality testing. The results showed that the level of foreign organic matter of simplicia was 1.34%, the fine degree of simplicia was 4/18 through mesh sieve number 4 100% and number 18 was 96%. Identity of the research sample Zingiber officinale Roscoe. The levels of compounds in simplicia that are soluble in water and ethanol are 16.86 ± 0.45% and 6.81 ± 0.23%. The levels of compounds in the extract that were soluble in water and ethanol were 13.55 ± 0.21% and 13.72 ± 0.16%. Drying loss of simplicia is 0.80 ± 0.52% and extract is 9.53 ± 0.25%. The water content for simplicia is 9.03 ± 0.64% and extract is 12.33 ± 1.53%. The specific gravity of the simplicia is 0.7849 ± 0.06 g/mL and the extract is 0.85 ± 0.09 g/mL. The total ash content of simplicia was 4.09 ± 0.97% and the extract was 3.63 ± 0.44%. The water-soluble ash content in simplicia is 2.17 ± 0.31% and the extract is 2.6 ± 0.26%. The insoluble ash content of simplicia acid was 1.11 ± 0.32% and the extract was 0.5 ± 0.46%. Testing the quality of simplicia and ginger rhizome extract met the requirements, namely all specific parameters as well as non-specific parameters (drying loss, total ash and acid insoluble ash).

References

Asworo, R.Y., dan Widwiastuti, H. Pengaruh Ukuran Serbuk Simplisia dan Waktu Maserasi terhadap Aktivitas Antioksidan Ekstrak Kulit Sirsak. Indonesian Journal of Pharmaceutical Education. 2023, 3(2), 256-263.

Burhan, A., Hardianti, B., dan Mujilah, M. Uji Aktivitas Hipoglikemik Ekstrak Daun Pisang Kepok Kering (Musa paradisiaca forma typica) Terhadap Mencit Jantan (Mus musculus). Media Kesehatan Politeknik Kesehatan Makassar, 2019, 14(1), 66-80.

Calixto, J. Efficacy, Safety, Quality Control, Marketing and Regulatory Guidelines for Herbal Medicines (Phytotherapeutic Agents). Brazilian Journal of Medical and Biological Research. 2000, 33(2), 179-189.

Chandra, P.P.B., Laksmitawati, D.R., dan Rahmat, D. Skrining Fitokimia dan Penetapan Kadar Flavonoid Total Ekstrak Buah Okra (Abelmoschus esculentus L.). Jurnal Kefarmasian Akfarindo. 2022, 7(2), 29-36.

Depkes RI. 2000. Parameter Standar Umum Ekstrak Tumbuhan Obat. Jakarta Indonesia: Departemen Kesehatan Republik Indonesia BPOM Dirjen Obat Tradisional Republik Indonesia.

Depkes RI. 2008. Farmakope Herbal Indonesia. I. Jakarta Indonesia: Departemen Kesehatan Republik Indonesia.

Ekayani, M., Juliantoni, Y., dan Hakim, A. Uji Efektivitas Larvasida dan Evaluasi Sifat Fisik Sediaan Losio Antinyamuk Ekstrak Etanol Daun Kirinyuh (Chromolaena odorata L.) Terhadap Nyamuk Aedes Aegypti. Jurnal Inovasi Penelitian. 2021, 2(4), 1261-1270.

Fatimawali, Kepel, B.J., dan Bodhi, W. Standarisasi Parameter Spesifik dan Non-Spesifik Ekstrak Rimpang Lengkuas Merah (Alpinia purpurata K. Sachum) sebagai Obat Antibakteri. Jurnal eBiomedik. 2020, 8(1), 63-67.

Harpina, J., Pratama, I.S., Hidayati, A.R, dan Wirasisya, D.G. Uji Aktivitas Antiaskariasis Seduhan dari Simplisia Daun Pecut Kuda (Stachytarpheta jamaicensis L. Vahl) Terstandar. Jurnal Sains dan Kesehatan. 2022, 4(5), 444-451.

Irma, S., Taebe, B., dan Noer, S. Standarisasi Parameter Non Spesifik Simplisia Ekstrak Etanol Rimpang Jahe Merah (Zingiber officinale roscoe var rubrum). Farbal: Jurnal Farmasi dan Bahan Alam. 2023, 11(2), 78-84.

Kemenkes RI. 2017. Farmakope Herbal Indonesia Edisi II. Kementerian Kesehatan Republik Indonesia. Jakarta.

Lestari, I.A.S. 2015. Pemeriksaan Makroskopik dan Mikroskopik Tanaman Meniran (Phyllanthus niruri L.). Karya Tulis Ilmiah. Fakultas Farmasi Universitas Sari Mutiara Indonesia, Medan, 6-7.

Mao, Q.Q., Xu, X.Y., Cao, S.Y., Gan, R.Y., Corke, H., Beta, T., and Li, H.B. Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe). Foods (Basel, Switzerland), 2019, 8(6), 1-21.

Permadi, T., Mulyani, R.D., dan Laurensia, V. Formulation of Antioxidant Syrup From The Combination of Sappan Wood (Caesalpinia sappan) and White Ginger (Curcumma mangga Val). Jurnal Ilmiah Farmako Bahari. 2022, 13(2), 176-183.

Pertiwi, R., Yudha, S.S, Prameswari, W., Aniza, M.V., Putri, B.A.N., dan Syahputra, R.A. Wisata Edukasi Tanaman Obat Tradisional di Pekarangan Wisata Alam Desa Rindu Hati. Surya Abdimas. 2022, 4(2), 415-422.

Rakhmawatie, M.D., dan Marfu’ati, N. Pembuatan Simplisia dan Teknik Penyiapan Obat Tradisional Jahe Merah dan Daun Pepaya untuk Standardisasi Dosis. Berdikari: Jurnal Inovasi dan Penerapan Ipteks. 2023, 11(1), 12-24.

Reubun, Y.T.A., Pangalila, A.A., Oktaviani, L., dan Siburian, O. Uji Parameter Spesifik dan Non Spesifik Ekstrak Benalu Teh (Scurrula oortiana Dans.). Parapemikir: Jurnal Ilmiah Farmasi. 2024, 13(1), 1-6.

Syahidan, H.H., dan Wardhana, Y.W. Review Jurnal: Parameter Standarisasi Tanaman Herbal Untuk Pengobatan. Jurnal Farmaka. 2019, 17(1), 263-272.

Utami, Y.P., Umar, A.H., Syahruni, R., dan Kadullah, I. Standardisasi Simplisia dan Ekstrak Etanol Daun Leilem (Clerodendrum minahassae Teisjm. & Binn.). Journal of Pharmaceutical and Medicinal Sciences. 2017, 2(1), 32-39.

Utami, Y.P. Pengukuran Parameter Simplisia Dan Ekstrak Etanol Daun Patikala (Etlingera elatior (Jack) R.M. Sm) Asal Kabupaten Enrekang Sulawesi Selatan. Majalah Farmasi dan Farmakologi. 2020, 24(1), 6-10.

Yoga, I.G.A.A., Kencana, P.K.D., dan Sumiyati, S. Pengaruh Lama Fermentasi dan Lama Pengeringan terhadap Karakteristik Teh Herbal Daun Bambu Tabah (Gigantochloa nigrociliata Buse - Kurz). Jurnal BETA (Biosistem dan Teknik Pertanian). 2021, 10(1), 71-80.