FORMULASI SEDIAAN HAIR TONIC EKSTRAK ETANOL DAUN KELOR (Moringa oleifera Lamk.) DAN DAUN RAMBUTAN (Nephelium lappaceaum L.) TERHADAP PERTUMBUHAN RAMBUT
Abstract
Moringa olifera lamk and Nephelium lappaceaum L leaves are empirically widely used to stimulate hair growth. The purpose of this research is to combine the kelor leaf extract and rambutan leaf extract formulated in hair tonic. The hair tonic preparations made were evaluated by performing a physical test of the preparation and knowing the best concentration of kelor leaf extract and rambutan leaf extract on rabbit hair growth. The hair tonic were orepared in 3 formulations with the ratio of kelor leaf exract and rambutan leaf extract (1:3 , 1:1 and 3:1)% w/v. the positive control used is hair tonic Minoxidil 2%. Physical tests of the preparation include organoleptic test, pH test, homogeneity test and Viscosity test. Hair growth activity on the 3 rabbits shaved hair and hair growth measurements until the 28 st day. The data of growth measurements were tested statistically by ANOVA test metode. Based on the reseach result, in can be concluded that hair tonic combination of kelor leaf extract and rambutan leaf extract with ratio (1:1)%, has average hair length 3 cm and hair weight 0,236 g is the optimum concentration in stimulating hair growth aktivity with positive control has average hair length 2,025 cm and hair weigth 0,207 g. Test statistically there was no significant difference between extract and positif control (P < 0,05).
References
Agoes, G. 2015. Buku Sediaan Kosmetik. Jakarta: ITB.
Aini, Q. Uji aktivitas pertumbuhan rambut kelinci jantan dari sediaan hair tonic yang mengandung ekstrak etanol daun Mangkokan (Nothopanax scutellarium L.). Jurnal Farmasi Lampung. 2017, 6(2): 1-12.
Alkandahri, M.Y., Berbudi, A., Utami, N.V., and Subarnas, A. Antimalarial activity of extract and fractions of Castanopsis costata (Blume) A.DC. Avicenna Journal of Phytomedicine. 2019, 9(5): 474-481.
Alkandahri, M.Y., Kusumiyati, K., Renggana, H., Arfania, M., Frianto, D., Wahyuningsih, ES., and Maulana, Y.E. Antihyperlipidemic activity of extract and fractions of Castanopsis costata leaves on rats fed with high cholesterol diet. RASĀYAN Journal of Chemistry. 2022, 15(4): 2350-2358.
Andriyani, D., Utami, P.I., dan Dhiani, B.A. Penetapan kadar tanin daun rambutan (Nephelium lappaceum. L) secara spektrofotometri ultraviolet visibel. Pharmacy 2010, 7(2): 1-11.
Dewatisari, W.F., Rumiyanti, L., and Rakhmawati, I. Rendemen dan skrining fitokimia pada ekstrak daun Sanseviera sp. Jurnal Penelitian Pertanian Terapan. 2018, 17(3): 197-202.
Fajriah, S., dan Megawati. Penapisan fitokimia dan uji toksisitas dari daun Myristica fatua Houtt. Chimica et Natura Acta. 2015, 3(3): 116-119.
Fakhrizal, M., dan Saputra, K. Potensi daun katuk dalam mencegah kerontokan rambut. Jurnal Penelitian Perawat Profesional. 2020, 2(2): 193-200.
Farhamzah, Kusumawati, A.H., Alkandahri, M.Y., Hidayah, H., Sujana, D., Gunarti, N.S., et al. Sun protection factor activity of Black Glutinous Rice emulgel extract (Oryza sativa var glutinosa). Indian Journal of Pharmaceutical Education and Research. 2022, 56(1): 302-310.
Hidayah, H., Amal, S., Yuniarsih, N., Farhamzah, Kusumawati, A.H., Gunarti, N.S., et al. Sun protection factor activity of jamblang leaves serum extract (Syzygium cumini). Pharmacognosy Journal. 2023, 15(1): 134-140.
Hindun, S. Formulation of hair tonic combination of celery and green tea leaves ethanol extract for rabbit hair growh. Jurnal Ilmiah Farmako Bahari. 2017, 8(1): 21-33.
Jubaidah, S., Indriani, R., Sa’adah, H., dan Wijaya, H. Formulasi dan uji pertumbuhan rambut kelinci dari sediaan hair tonic kombinasi ekstrak daun seledri (Apium graveolens Linn) dan daun mangkokan (Polyscias scutellaria (Burm.f.) Fosberg. Jurnal Ilmiah Manuntung. 2018, 4(1): 8-14.
Khoironi, N. 2013. Karakterisasi simplisia dan standarisasi ekstrak etanol herba kemangi (Ocimum americanum L.). (Skripsi). Fakultas Kedokteran dan Ilmu Kesehatan UIN Syarif Hidayatullah. Jakarta.
Kuncari, E.S. 2014. Uji iritasi dan aktivitas pertumbuhan rambut tikus putih : efek sediaan gel apigenin dan perasan herba seledri (Apium graveolens L.). Media Litbangkes. 2014, 25(1): 15-22.
Meigaria, K.M., Mudianta, I.W., dan Martiningsih, N.W. Skrining fitokimia dan uji aktivitas antioksidan ekstrak aseton daun kelor (Moringa oleifera). Jurnal Wahana Matematika dan Sains. 2016, 10(1): 1-11.
Muliani, W, Setiawan, F., dan Sukmawan, Y.P. Formulasi dan evaluasi sediaan hair tonic ekstrak etanol daun Katuk (Sauropus androgynus (L.) Merr.) sebagai pertumbuhan rambut pada kelinci jantan New Zealand white. Prosiding Seminar Nasional Diseminasi. 2022, 2: 101-112.
Nurbaya, S., dan Silalahi, Y.C.E. Penggunaan daun kelor (Moringao oleifera) sebagai sediaan hair tonic. Jurnal Farmanesia. 2017, 4(1): 1-9.
Shafirany, M.Z., Indawati, I., Sulastri, L., Sadino, A., Kusumawati, A.H., and Alkandahri, MY. Antioxidant activity of red and purple rosella flower petals extract (Hibiscus sabdariffa L.). Journal of Pharmaceutical Research International. 2021, 33(46B): 186-192.
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