FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN FOOTSPRAY ANTI BAU KAKI EKSTRAK TEH HITAM (Camellia sinensis) DAN DAUN JAMBU BIJI (Psidium guajava L.)
Abstract
Increased release of apocrine infected by bacteria during the decay process will result in foot odor or bromhidrosis. Foot odor is caused by skin microbes. Some of the bacteria that cause foot odor are Staphylococcus epidermidis and Staphylococcus aureus. Black tea and guava leaves are natural ingredients that contain antibacterial compounds, namely flavonoids, saponins, tannins and alkaloids. The purpose of this study was to formulate footspray preparations from extracts of black tea and guava leaves and to determine the antibacterial activity of each formulation. This study uses an experimental method. Extracts of black tea and guava leaves are produced from the maceration extraction process, then the resulting extract is formulated into footspray with various concentrations. Footspray preparations were tested for evaluation of physical preparations and tested for antibacterial activity of Staphylococcus epidermidis and Staphylococcus aureus by the paper disc method. The results showed that black tea and guava leaf extracts could be formulated as active substances in footspray preparations which had antibacterial activity which was indicated by the presence of clear zones in formulas 1, 2 and 3. However, in the control formula there was no antibacterial activity which was indicated by the absence of clear zone.
References
Ashfia, F., Adriane, F.Y., Sari., D.P., dan Rusmini. Formulasi dan Uji Aktivitas Antibakteri Sediaan Footspray Anti Bau Kaki yang Mengandung Ekstrak Kulit Jeruk Nipis dan Ampas Kopi. Indonesian Chemisry and Application Journal. 2019, 3(1), 28-33.
Djoko, W., Taurhesia, S., Djamil, R., dan Simanjuntak, P. Standardisasi Ekstrak Etanol Herba Pegagan (Centella asiatica). Saintech Farma: Jurnal Ilmu Kefarmasian. 2020, 13(2), 118-123.
Farhamzah, Kusumawati, A.H., Alkandahri, M.Y., Hidayah, H., Sujana, D., Gunarti, N.S. et al. Sun Protection Factor Activity of Black Glutinous Rice Emulgel Extract (Oryza sativa var glutinosa). Indian Journal of Pharmaceutical Education and Research. 2022, 56(1): 302-310.
Halid, I., Asio, dan Fitria, K.T. Efektivitas Air Seduhan Teh Hitam (Camellia sinensis) Dalam Menurunkan Akumulasi Plak. Jurnal Bahana Kesehatan Masyarakat. 2021, 5(1), 54-60.
Handarni, D., Putri, S.H., dan Tensiska. Skrinning Kualitatif Fitokimia Senyawa Antibakteri pada Ekstrak Daun Jambu Biji (Psidiium guajava L.). Jurnal Keteknikan Pertanian Tropis dan Biosistem. 2020, 8(2), 182-188.
Kusumawati, A.H., Farhamzah, F., Alkandahri, M.Y., Sadino, A., Agustina, L.S., and Apriana, S.D. Antioxidant Activity and Sun Protection Factor of Black Glutinous Rice (Oryza sativa var. glutinosa). Tropical Journal of Natural Product Research. 2021, 5(11), 1958-1961.
Maulidina, V. 2020. Aktivitas Antibakteri Ekstrak Daun Teh (Camellia sinensis (L.) Kuntze) Terhadap Bakteri Streptococcus pneumonia Resistan Makrolida. Skripsi. Fakultas Sains dan Teknologi Universitas Islam Negeri Hidayatullah, Jakarta.
Niken, Yusuf, R.N., dan Annita. Uji Aktivitas Antibakteri Ekstrak Daun Jambu Biji (Psidium guajava L.) Terhadap Pertumbuhan Bakteri Escherichia coli. Bioscientist: Jurnal Ilmiah Biologi. 2022, 10(2), 726-735.
Nuraeni, E., Alkandahri, M.Y., Tanuwidjaja, S.M., Fadhilah, K.N., Kurnia, G.S., Indah, D., et al. Ethnopharmacological Study of Medicinal Plants in the Rawamerta Region Karawang, West Java, Indonesia. Open Access Macedonian Journal of Medical Sciences. 2022, 10(A), 1560-1564.
Risnayanti dan Dalimunthe, G.I. 2022. Formulasi Footspray Esktrak Daun Kemangi (Ocimum africanum L.) Sebagai Penghilang Bau Kaki Serta Uji Aktivitas Antibakteri. Jurnal Farmasi Sains dan Kesehatan. 2022, 1(2), 115-123.
Solihah, Y.S., dan Hidayat, F. Pengaruh Metode Plasma Dalam Peningkatan Penyerapan Minyak Kayu Manis (Cinnamon oil) pada Kaos Kaki dan Uji Aktivitas Antibakteri Terhadap Staphylococcus epidermis. Jurnal Riset Farmasi. 2021, 1(2), 124-132.
Ulfa, A.M., Nofita, dan Sandi, B.S. Uji Aktivitas Antibakteri Spray Bau Kaki Ekstrak Kulit Jeruk Nipis (Citrus aurantifolia) dengan Variasi Gelling Agent Terhadap Bakteri Bacillus subtilis. Jurnal Farmasi Lampung. 2020, 9(1), 18-26.
Wahyuningsih, E.S., Puspitasari, M., Gunarti, N.S., Alkandahri, M.Y. Uji Aktivitas Antibakteri Face Mist Ekstrak Etanol Daun Andong Merah (Cordyline fruticosa (L) A. Chev.) Terhadap Propionibacterium acnes. Pharma Xplore: Jurnal Sains dan Ilmu Farmasi. 2023, 8(2), 104-127.
Widaty, S.H., Soebono, H., Nilasari, Y., Listiawan, A.S., dan Siswanti, D. Panduan Praktik Klinik Dokter Spesialis Kulit dan Kelamin di Indonesia. Perdoksi. 2017, 2(3), 260-265.
Widiani, P.I., dan Pinatih, K.J.P. Uji Daya Hambat Ekstrak Etanol Daun Kelor (Moringa oleifera) Terhadap Pertumbuhan Bakteri Methicillin Resistant Staphylococcus aureus (MRSA). Medika Udayana. 2020, 9(3), 22-28.
Yuniarsih, N., Hidayah, H., Gunarti, N.S., Kusumawati, A.H., Farhamzah, F., Sadino, A., et al. Evaluation of Wound-Healing Activity of Hydrogel Extract of Sansevieria trifasciata Leaves (Asparagaceae). Advances in Pharmacological and Pharmaceutical Sciences. 2023; 2023 (Article ID 7680518): 1-10.
Zauharoh, R., Fadholah, A., dan Khotimah, M.S.H. Uji Efektivitas Ekstrak Etanol Teh Hijau (Camellia sinensis) Terhadap Penyembuhan Luka Sayat Pada Kulit Tikus. Pharmaceutical Journal of Islamic Pharmacy. 2022, 4(2), 24-29.
Zulkarnaen, P., Fadila, N., Fadhilah, L.N., Kartika, Kardila, K., Laely, N., et al. Pharmacological Activity of Selaginella doederleinii Hieron: An Updated Review. European Journal of Pharmaceutical and Medical Research. 2024, 11(3), 17-20
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